ALS Curtis Vance Foundation - Page 7 of 21 - ALS Disease Facts and Information

Sudden Death from ALS: Unraveling the Mystery

9 Jan 2024admin_alscvf8679Leave a comment

Sudden death from ALS, an abbreviation for amyotrophic lateral sclerosis, stands as a devastating reality faced by individuals grappling with …

Bulbar ALS Symptoms: An Overview of the Debilitating Condition

7 Dec 2023admin_alscvf8679Leave a comment

Bulbar ALS symptoms encompass a distinct subset of factors associated with Amyotrophic Lateral Sclerosis (ALS), a challenging neurodegenerative disease. This …

What is Bulbar ALS: Symptoms, and Diagnosis

8 Nov 2023admin_alscvf8679Leave a comment

When we delve into the realm of neurodegenerative diseases, certain terms frequently emerge, cloaked in medical complexity and human concern. …

Other Informations About Neurons

Polarized Signaling Endosomes Coordinate BDNF-Induced Chemotaxis of Cerebellar Precursors 11/15/2025

(Neuron 55, 53–68; July 5, 2007)

Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution 11/14/2025

Hypertension is a major cause of cognitive decline, but the underlying mechanisms are unclear. Using scRNA-seq in an angiotensin II mouse model, Schaeffer and Pacholko identify early endothelial, interneuron, and oligodendrocyte vulnerability linked to angiotensin II signaling, revealing molecular pathways that drive later neurovascular dysfunction and cognitive impairment in hypertension.

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism 11/13/2025

Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these claims and find them conceptually and methodologically flawed.

Globally patterned locus coeruleus-norepinephrine neuron-pericyte coupling orchestrates brain-wide vascular dynamics 11/12/2025

Through whole-brain neurovascular imaging in larval zebrafish, Sun and Peng et al. show that the locus coeruleus-norepinephrine (LC-NE) system orchestrates globally patterned pericyte activities through complementary direct NE and indirect glia-relayed actions. Such LC-NE neuron-pericyte coupling exerts global vasoconstrictive drives that coordinate blood flow and support sustained behavioral performance.