ALS Curtis Vance Foundation - Page 7 of 21 - ALS Disease Facts and Information

Sudden Death from ALS: Unraveling the Mystery

9 Jan 2024admin_alscvf8679Leave a comment

Sudden death from ALS, an abbreviation for amyotrophic lateral sclerosis, stands as a devastating reality faced by individuals grappling with …

Bulbar ALS Symptoms: An Overview of the Debilitating Condition

7 Dec 2023admin_alscvf8679Leave a comment

Bulbar ALS symptoms encompass a distinct subset of factors associated with Amyotrophic Lateral Sclerosis (ALS), a challenging neurodegenerative disease. This …

What is Bulbar ALS: Symptoms, and Diagnosis

8 Nov 2023admin_alscvf8679Leave a comment

When we delve into the realm of neurodegenerative diseases, certain terms frequently emerge, cloaked in medical complexity and human concern. …

Other Informations About Neurons

Unifying the structures of language in a neural population code 08/14/2026

How does language emerge from neural computations in the human brain? In stark contrast to symbolic theories of language, large language models demonstrate how the structures of language can be unified in a high-dimensional neural population code.

Astrocytic NFIX regulates thalamocortical circuits through GABA and purinergic signaling 08/13/2026

Astrocytes play essential roles in brain function by supporting neural circuits and cognition. Murali et al. find that the transcription factor NFIX is required to maintain astrocyte function in the thalamic reticular nucleus through region-specific control of GABA signaling. Altered astrocyte-neuron communication disrupts thalamocortical oscillations, impairing learning and memory.

Status-dependent competition engagement via mesocortical pathway 08/12/2026

Jin et al. establish the win maze to study how mice decide to re-engage in competition after winning outcomes. They show that dominant males display stronger competition engagement, with dmPFC neural dynamics predicting future choices and mesocortical dopamine bidirectionally regulating engagement.

Developmentally defined subcircuits in the hippocampus support spatial learning 08/12/2026

Huszár, Kirsanov et al. show that hippocampal CA3 and CA1 neurons born on the same day form a functional subcircuit that encodes new memories. Spatial learning engaged convergent connectivity from embryonically related pyramidal neurons onto parvalbumin-expressing CA1 interneurons.