ALS Curtis Vance Foundation - Page 9 of 21 - ALS Disease Facts and Information

How To Prevent ALS: What Is The Possibility?

9 Mar 2023admin_alscvf8679Leave a comment

It’s estimated that approximately 20,000 individuals in the US currently suffer from amyotrophic lateral sclerosis (ALS). Although there is no …

Life With ALS: The Stephen Hawking Story

24 Feb 2023admin_alscvf8679Leave a comment

Stephen William Hawking is one of the most influential and inspirational figures of modern times. Diagnosed with a neuromuscular disease …

Signs You Don’t Have ALS and How to Tell if You’re At Risk

16 Jan 2023admin_alscvf8679Leave a comment

Most people have never heard of Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease. It is a rare …

Other Informations About Neurons

Polarized Signaling Endosomes Coordinate BDNF-Induced Chemotaxis of Cerebellar Precursors 11/15/2025

(Neuron 55, 53–68; July 5, 2007)

Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution 11/14/2025

Hypertension is a major cause of cognitive decline, but the underlying mechanisms are unclear. Using scRNA-seq in an angiotensin II mouse model, Schaeffer and Pacholko identify early endothelial, interneuron, and oligodendrocyte vulnerability linked to angiotensin II signaling, revealing molecular pathways that drive later neurovascular dysfunction and cognitive impairment in hypertension.

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism 11/13/2025

Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these claims and find them conceptually and methodologically flawed.

Globally patterned locus coeruleus-norepinephrine neuron-pericyte coupling orchestrates brain-wide vascular dynamics 11/12/2025

Through whole-brain neurovascular imaging in larval zebrafish, Sun and Peng et al. show that the locus coeruleus-norepinephrine (LC-NE) system orchestrates globally patterned pericyte activities through complementary direct NE and indirect glia-relayed actions. Such LC-NE neuron-pericyte coupling exerts global vasoconstrictive drives that coordinate blood flow and support sustained behavioral performance.