ALS Curtis Vance Foundation - Page 9 of 21 - ALS Disease Facts and Information

How To Prevent ALS: What Is The Possibility?

9 Mar 2023admin_alscvf8679Leave a comment

It’s estimated that approximately 20,000 individuals in the US currently suffer from amyotrophic lateral sclerosis (ALS). Although there is no …

Life With ALS: The Stephen Hawking Story

24 Feb 2023admin_alscvf8679Leave a comment

Stephen William Hawking is one of the most influential and inspirational figures of modern times. Diagnosed with a neuromuscular disease …

Signs You Don’t Have ALS and How to Tell if You’re At Risk

16 Jan 2023admin_alscvf8679Leave a comment

Most people have never heard of Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease. It is a rare …

Other Informations About Neurons

Unifying the structures of language in a neural population code 08/14/2026

How does language emerge from neural computations in the human brain? In stark contrast to symbolic theories of language, large language models demonstrate how the structures of language can be unified in a high-dimensional neural population code.

Astrocytic NFIX regulates thalamocortical circuits through GABA and purinergic signaling 08/13/2026

Astrocytes play essential roles in brain function by supporting neural circuits and cognition. Murali et al. find that the transcription factor NFIX is required to maintain astrocyte function in the thalamic reticular nucleus through region-specific control of GABA signaling. Altered astrocyte-neuron communication disrupts thalamocortical oscillations, impairing learning and memory.

Status-dependent competition engagement via mesocortical pathway 08/12/2026

Jin et al. establish the win maze to study how mice decide to re-engage in competition after winning outcomes. They show that dominant males display stronger competition engagement, with dmPFC neural dynamics predicting future choices and mesocortical dopamine bidirectionally regulating engagement.

Developmentally defined subcircuits in the hippocampus support spatial learning 08/12/2026

Huszár, Kirsanov et al. show that hippocampal CA3 and CA1 neurons born on the same day form a functional subcircuit that encodes new memories. Spatial learning engaged convergent connectivity from embryonically related pyramidal neurons onto parvalbumin-expressing CA1 interneurons.