ALS Curtis Vance Foundation - Page 6 of 21 - ALS Disease Facts and Information

ALS vs Muscular Dystrophy: Unpacking the Differences

4 Apr 2024admin_alscvf8679Leave a comment

Navigating the complexities of neurological disorders, particularly when comparing ALS vs muscular dystrophy, requires a deep dive into the nuances …

ALS Hand Atrophy: Understanding the Impact and Management Strategies

7 Mar 2024admin_alscvf8679Leave a comment

Amyotrophic Lateral Sclerosis (ALS) is a progressive disease that deteriorates motor neurons in the brain and spinal cord, resulting in …

Is ALS Autoimmune: The Link Between Amyotrophic Lateral Sclerosis and the Immune System

7 Feb 2024admin_alscvf8679Leave a comment

ALS, Amyotrophic lateral sclerosis, commonly known as Lou Gehrig’s disease, is a debilitating neurodegenerative disorder that has puzzled researchers and …

Other Informations About Neurons

Polarized Signaling Endosomes Coordinate BDNF-Induced Chemotaxis of Cerebellar Precursors 11/15/2025

(Neuron 55, 53–68; July 5, 2007)

Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution 11/14/2025

Hypertension is a major cause of cognitive decline, but the underlying mechanisms are unclear. Using scRNA-seq in an angiotensin II mouse model, Schaeffer and Pacholko identify early endothelial, interneuron, and oligodendrocyte vulnerability linked to angiotensin II signaling, revealing molecular pathways that drive later neurovascular dysfunction and cognitive impairment in hypertension.

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism 11/13/2025

Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these claims and find them conceptually and methodologically flawed.

Globally patterned locus coeruleus-norepinephrine neuron-pericyte coupling orchestrates brain-wide vascular dynamics 11/12/2025

Through whole-brain neurovascular imaging in larval zebrafish, Sun and Peng et al. show that the locus coeruleus-norepinephrine (LC-NE) system orchestrates globally patterned pericyte activities through complementary direct NE and indirect glia-relayed actions. Such LC-NE neuron-pericyte coupling exerts global vasoconstrictive drives that coordinate blood flow and support sustained behavioral performance.